Reactive airway disease

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Reactive Airways Dysfunction Syndrome or RADS (also known as Reactive Airway Disease or RAD) is a term proposed by S.M. Brooks and colleagues in 1985 [1] to describe an asthma-like syndrome developing after a single exposure to high levels of an irritating vapor, fume, or smoke.[2] In time, however, it has evolved to be mistakenly used as a synonym for asthma[3]. Current usage of the term in the medical community is to describe an asthma-like syndrome in infants that may later be confirmed to be asthma when they become old enough to participate in diagnostic tests such as the methacholine challenge test. It can also manifest in adults with exposure to high levels of Chlorine gas, creating symptoms like asthma. The severity of these symptoms can be mild to fatal, and can even create long term airway damage depending on the amount of exposure and the concentration of Chlorine. Some experts classify RADS as occupational asthma. Those with exposure to high irritating substances should receive treatment to mitigate harmful effects. [4]

[edit] References

  1. ^ S.M. Brooks, M.A. Weiss, I.L. Bernstein. Reactive airways dysfunction syndrome (RADS): persistent asthma syndrome after high level irritant exposures. Chest, Volume 88, 1985, 376-384. Retrieved on 2007-08-28.
  2. ^ John V. Fahy and Paul M. O'Byrne. "Reactive Airways Disease": A Lazy Term of Uncertain Meaning That Should Be Abandoned. Am. J. Respir. Crit. Care Med., Volume 163, Number 4, March 2001, 822-823. Retrieved on 2007-04-22.
  3. ^ Mayo Clinic Staff (Sep 4, 2006). Reactive airway disease: Is it asthma?. Mayo Clinic. Retrieved on 2007-04-22.
  4. ^ Aslan, Sahin1Kandiş, Hayati1Akgun, Metin2Çakır, Zeynep1Inandı, Tacettin3Görgüner, Metin. The Effect of Nebulized NaHCO3 Treatment on 'RADS' Due to Chlorine Gas Inhalation. Inhalation Toxicology., Volume 18, Number 11, 2006,895-900. Retrieved on 2008-04-06.