Raymond Hamers

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Raymond Hamers is a professor at the Vrije Universiteit Brussel (Brussels, Belgium). He discovered a special type of antibodies: Nanobodies

In 1989 a group of biologists led by Raymond Hamers at the Free University investigated an odd observation handed in as part of a student project on how dromedary camels (the one-humped, Arabian variety) and water buffalo fight off parasites. One of the tests for antibodies in the dromedary blood seemed to show an error: in addition to normal four-chain antibodies, it indicated the presence of simpler antibodies composed solely of a pair of heavy chains.

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  • Hamers-Casterman C, Atarhouch T, Muyldermans S, Robinson G, Hamers C, Songa EB, Bendahman N, Hamers R., Naturally occurring antibodies devoid of light chains, Nature. 1993 Jun 3;363(6428):446-8.
  • Matthyssens G et al., Two variant surface glycoproteins of Trypanosoma brucei have a conserved C-terminus, Nature, 293, 230-233, 1981
  • Strosberg AD et al., A rabbit with the allotypic phenotype: ala2a3 b4b5b6, J Immunol, 113, 1313-1318, 1974