Raphaël Lépine

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Raphaël Lépine (July 6, 1840 - November 17, 1919) was a French physiologist who was a native of Lyon. He studied under Jean-Martin Charcot (1825-1893) in Paris, and afterwards worked in hospitals in Paris and Lyon. In 1877 he became professor of clinical medicine at l’Hôtel-Dieu de Lyon. He was the brother of prefect Louis Lépine (1846-1933), creator of the "Concours Lépine". Two of his better-known students were Frédéric Justin Collet (1870-1966) and Léon Bouveret (1850-1929).

Raphaël Lépine is known for his studies in experimental medicine, particularly his research involving the pathophysiology of diabetes, and his investigations of blood sugar and glycogenesis. He made important contributions in the study of internal secretions of the pancreas, and did extensive research of glycosuria. Among his written works were two influential works on diabetes called Les complications du diabète et leur traitement and Le diabète non compliqué et son traitement.