RAB8B

From Wikipedia, the free encyclopedia

RAB8B, member RAS oncogene family

Identifiers

RAB8B; FLJ38125

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • ATP binding • GTP binding • transcription factor binding
Cellular Component:	• cellular_component • intracellular • membrane
Biological Process:	• regulation of transcription, DNA-dependent • small GTPase mediated signal transduction • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_016530 (mRNA)
NP_057614 (protein)

NM_173413 (mRNA)
NP_775589 (protein)

Location

Chr 15: 61.27 - 61.35 Mb

n/a

Pubmed search

[1]

[2]

RAB8B, member RAS oncogene family, also known as RAB8B, is a human gene.^[1]

[edit] References

^ Entrez Gene: RAB8B RAB8B, member RAS oncogene family.

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lau AS, Mruk DD (2003). "Rab8B GTPase and junction dynamics in the testis.". Endocrinology 144 (4): 1549-63. PMID 12639940.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Hattula K, Furuhjelm J, Arffman A, Peränen J (2003). "A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.". Mol. Biol. Cell 13 (9): 3268-80. doi:10.1091/mbc.E02-03-0143. PMID 12221131.
de Bruyn KM, de Rooij J, Wolthuis RM, et al. (2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral.". J. Biol. Chem. 275 (38): 29761-6. doi:10.1074/jbc.M001160200. PMID 10889189.
Chen D, Guo J, Gahl WA (1997). "RAB GTPases expressed in human melanoma cells.". Biochim. Biophys. Acta 1355 (1): 1-6. PMID 9030196.
Armstrong J, Thompson N, Squire JH, et al. (1997). "Identification of a novel member of the Rab8 family from the rat basophilic leukaemia cell line, RBL.2H3.". J. Cell. Sci. 109 ( Pt 6): 1265-74. PMID 8799816.