RAB6C

From Wikipedia, the free encyclopedia

RAB6C, member RAS oncogene family

PDB rendering based on 1yzq.

Available structures: 1yzq

Identifiers

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • GTP binding
Cellular Component:	• intracellular
Biological Process:	• small GTPase mediated signal transduction • protein transport • response to drug

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

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Refseq

NM_032144 (mRNA)
NP_115520 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 2: 130.45 - 130.46 Mb

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Pubmed search

[1]

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RAB6C, member RAS oncogene family, also known as RAB6C, is a human gene.^[1]

[edit] References

^ Entrez Gene: RAB6C RAB6C, member RAS oncogene family.

[edit] Further reading

"Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097–108. PMID 9847074.
Fitzgerald ML, Reed GL (1999). "Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution.". Biochem. J. 342 ( Pt 2): 353–60. PMID 10455022.
Shan J, Mason JM, Yuan L, et al. (2001). "Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells.". Gene 257 (1): 67–75. PMID 11054569.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Shan J, Yuan L, Budman DR, Xu HP (2002). "WTH3, a new member of the Rab6 gene family, and multidrug resistance.". Biochim. Biophys. Acta 1589 (2): 112–23. PMID 12007787.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Tian K, Jurukovski V, Wang XP, et al. (2005). "Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells.". Cancer Res. 65 (21): 10024–31. doi:10.1158/0008-5472.CAN-05-1944. PMID 16267028.
Tian K, Wang Y, Xu H (2007). "WTH3 is a direct target of the p53 protein.". Br. J. Cancer 96 (10): 1579–86. doi:10.1038/sj.bjc.6603724. PMID 17426708.