RAB3B

From Wikipedia, the free encyclopedia

RAB3B, member RAS oncogene family

Identifiers

External IDs

OMIM: 179510 MGI: 1917158 HomoloGene: 2149

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • protein binding • GTP binding
Cellular Component:	• synaptic vesicle • membrane • dense core granule
Biological Process:	• small GTPase mediated signal transduction • protein transport • regulation of exocytosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002867 (mRNA)
NP_002858 (protein)

NM_023537 (mRNA)
NP_076026 (protein)

Location

Chr 1: 52.15 - 52.23 Mb

Chr 4: 108.39 - 108.44 Mb

Pubmed search

[1]

[2]

RAB3B, member RAS oncogene family, also known as RAB3B, is a human gene.^[1]

[edit] References

^ Entrez Gene: RAB3B RAB3B, member RAS oncogene family.

[edit] Further reading

Rousseau-Merck MF, Zahraoui A, Touchot N, et al. (1991). "Chromosome assignment of four RAS-related RAB genes.". Hum. Genet. 86 (4): 350–4. PMID 1999336.
Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.". J. Biol. Chem. 264 (21): 12394–401. PMID 2501306.
Weber E, Berta G, Tousson A, et al. (1994). "Expression and polarized targeting of a rab3 isoform in epithelial cells.". J. Cell Biol. 125 (3): 583–94. PMID 8175882.
Weber E, Jilling T, Kirk KL (1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells.". J. Biol. Chem. 271 (12): 6963–71. PMID 8636125.
Regazzi R, Ravazzola M, Iezzi M, et al. (1997). "Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells.". J. Cell. Sci. 109 ( Pt 9): 2265–73. PMID 8886977.
Sidhu RS, Bhullar RP (2002). "Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin.". Biochem. Biophys. Res. Commun. 289 (5): 1039–43. doi:10.1006/bbrc.2001.6113. PMID 11741295.
van IJzendoorn SC, Tuvim MJ, Weimbs T, et al. (2002). "Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells.". Dev. Cell 2 (2): 219–28. PMID 11832247.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
Yamamoto Y, Nishimura N, Morimoto S, et al. (2003). "Distinct roles of Rab3B and Rab13 in the polarized transport of apical, basolateral, and tight junctional membrane proteins to the plasma membrane.". Biochem. Biophys. Res. Commun. 308 (2): 270–5. PMID 12901864.
Matsumoto M, Miki T, Shibasaki T, et al. (2004). "Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells.". Proc. Natl. Acad. Sci. U.S.A. 101 (22): 8313–8. doi:10.1073/pnas.0306709101. PMID 15159548.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.