RAB21

From Wikipedia, the free encyclopedia

RAB21, member RAS oncogene family

PDB rendering based on 1yzt.

Available structures: 1yzt, 1yzu, 1z08, 1z0i, 2ot3

Identifiers

Symbol(s)

RAB21; KIAA0118

External IDs

MGI: 894308 HomoloGene: 8991

Gene ontology
Molecular Function:	• nucleotide binding • GTP binding
Cellular Component:	• endosome
Biological Process:	• small GTPase mediated signal transduction • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014999 (mRNA)
NP_055814 (protein)

NM_024454 (mRNA)
NP_077774 (protein)

Location

Chr 12: 70.43 - 70.47 Mb

Chr 10: 114.69 - 114.72 Mb

Pubmed search

[1]

[2]

RAB21, member RAS oncogene family, also known as RAB21, is a human gene.^[1]

[edit] References

^ Entrez Gene: RAB21 RAB21, member RAS oncogene family.

[edit] Further reading

Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 2 (1): 37–43. PMID 7788527.
Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects.". Horm. Metab. Res. 30 (11): 656–62. PMID 9918381.
Opdam FJ, Kamps G, Croes H, et al. (2000). "Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells.". Eur. J. Cell Biol. 79 (5): 308–16. PMID 10887961.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Pereira-Leal JB, Seabra MC (2001). "Evolution of the Rab family of small GTP-binding proteins.". J. Mol. Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.
Pellinen T, Arjonen A, Vuoriluoto K, et al. (2006). "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.". J. Cell Biol. 173 (5): 767–80. doi:10.1083/jcb.200509019. PMID 16754960.