R-linalool synthase

From Wikipedia, the free encyclopedia

In enzymology, a R-linalool synthase (EC 4.2.3.26) is an enzyme that catalyzes the chemical reaction

geranyl diphosphate + H₂O (3R)-linalool + diphosphate

Thus, the two substrates of this enzyme are geranyl diphosphate and H₂O, whereas its two products are (3R)-linalool and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming]. Other names in common use include (3R)-linalool synthase, and (-)-3R-linalool synthase.

[edit] References

• IUBMB entry for 4.2.3.26
• BRENDA references for 4.2.3.26 (Recommended.)
• PubMed references for 4.2.3.26
• PubMed Central references for 4.2.3.26
• Google Scholar references for 4.2.3.26
• Jia JW, Crock J, Lu S, Croteau R, Chen XY (1999). "(3R)-Linalool synthase from Artemisia annua L.: cDNA isolation, characterization, and wound induction". Arch. Biochem. Biophys. 372: 143–9. doi:10.1006/abbi.1999.1466. PMID 10562427. 
• Crowell AL, Williams DC, Davis EM, Wildung MR, Croteau R (2002). "Molecular cloning and characterization of a new linalool synthase". Arch. Biochem. Biophys. 405: 112–21. doi:10.1016/S0003-9861(02)00348-X. PMID 12176064. 

[edit] External links

• IUBMB entry for 4.2.3.26

• KEGG entry for 4.2.3.26

• BRENDA entry for 4.2.3.26

• NiceZyme view of 4.2.3.26

• EC2PDB: PDB structures for 4.2.3.26

• PRIAM entry for 4.2.3.26

• PUMA2 entry for 4.2.3.26

• IntEnz: Integrated Enzyme entry for 4.2.3.26

• MetaCyc entry for 4.2.3.26

• Atomic-resolution structures of enzymes belonging to this class