Quaternary-amine-transporting ATPase

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In enzymology, a quaternary-amine-transporting ATPase (EC 3.6.3.32) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + quaternary amineout $\rightleftharpoons$ ADP + phosphate + quaternary aminein

The 3 substrates of this enzyme are ATP, H₂O, and quaternary amine, whereas its 3 products are ADP, phosphate, and quaternary amine.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (quaternary-amine-importing). This enzyme participates in abc transporters - general.

[edit] References

IUBMB entry for 3.6.3.32
BRENDA references for 3.6.3.32 (Recommended.)
PubMed references for 3.6.3.32
PubMed Central references for 3.6.3.32
Google Scholar references for 3.6.3.32
Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146: 271–8. PMID 7569321.
Kempf B, Gade J, Bremer E (1997). "Lipoprotein from the osmoregulated ABC transport system OpuA of Bacillus subtilis: purification of the glycine betaine binding protein and characterization of a functional lipidless mutant". J. Bacteriol. 179: 6213–20. PMID 9335265.
Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977.