Pyrogallol hydroxytransferase
From Wikipedia, the free encyclopedia
In enzymology, a pyrogallol hydroxytransferase (EC 1.97.1.2) is an enzyme that catalyzes the chemical reaction
- 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene
1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene
Thus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene, whereas its two products are 1,3,5-trihydroxybenzene and 1,2,3,5-tetrahydroxybenzene.
This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase. Other names in common use include 1,2,3,5-tetrahydroxybenzene hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase, 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase), pyrogallol hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase. This enzyme participates in benzoic acid degradation via CoA ligation.
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[edit] Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1TI2, 1TI4, 1TI6, 1VLD, 1VLE, and 1VLF.
[edit] References
- IUBMB entry for 1.97.1.2
- BRENDA references for 1.97.1.2 (Recommended.)
- PubMed references for 1.97.1.2
- PubMed Central references for 1.97.1.2
- Google Scholar references for 1.97.1.2
- Brune A, Schink B (1990). "Pyrogallol-to-phloroglucinol conversion and other hydroxyl-transfer reactions catalyzed by cell extracts of Pelobacter acidigallici". J. Bacteriol. 172: 1070–6. PMID 2298693.
[edit] External links
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- The CAS registry number for this enzyme class is 125978-84-9.
[edit] Gene Ontology (GO) codes
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