Pyrogallol 1,2-oxygenase

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In enzymology, a pyrogallol 1,2-oxygenase (EC 1.13.11.35) is an enzyme that catalyzes the chemical reaction

1,2,3-trihydroxybenzene + O₂ (Z)-5-oxohex-2-enedioate

Thus, the two substrates of this enzyme are 1,2,3-trihydroxybenzene and O₂, whereas its product is (Z)-5-oxohex-2-enedioate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is 1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing). This enzyme is also called pyrogallol 1,2-dioxygenase.

[edit] References

• IUBMB entry for 1.13.11.35
• BRENDA references for 1.13.11.35 (Recommended.)
• PubMed references for 1.13.11.35
• PubMed Central references for 1.13.11.35
• Google Scholar references for 1.13.11.35
• Groseclose EE, Ribbons DW (1981). "Metabolism of resorcinylic compounds by bacteria: new pathway for resorcinol catabolism in Azotobacter vinelandii". J. Bacteriol. 146: 460–6. PMID 7217008. 

[edit] External links

The CAS registry number for this enzyme class is 78310-68-6.

• IUBMB entry for 1.13.11.35

• KEGG entry for 1.13.11.35

• BRENDA entry for 1.13.11.35

• NiceZyme view of 1.13.11.35

• EC2PDB: PDB structures for 1.13.11.35

• PRIAM entry for 1.13.11.35

• PUMA2 entry for 1.13.11.35

• IntEnz: Integrated Enzyme entry for 1.13.11.35

• MetaCyc entry for 1.13.11.35

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050240: pyrogallol 1,2-oxygenase

• AMIGO entry for GO code 0050240: pyrogallol 1,2-oxygenase