Pyrimidine-5'-nucleotide nucleosidase

From Wikipedia, the free encyclopedia

In enzymology, a pyrimidine-5'-nucleotide nucleosidase (EC 3.2.2.10) is an enzyme that catalyzes the chemical reaction

a pyrimidine 5'-nucleotide + H₂O D-ribose 5-phosphate + a pyrimidine base

Thus, the two substrates of this enzyme are pyrimidine 5'-nucleotide and H₂O, whereas its two products are D-ribose 5-phosphate and pyrimidine base.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase. Other names in common use include pyrimidine nucleotide N-ribosidase, and Pyr5N. This enzyme participates in pyrimidine metabolism.

[edit] References

• IUBMB entry for 3.2.2.10
• BRENDA references for 3.2.2.10 (Recommended.)
• PubMed references for 3.2.2.10
• PubMed Central references for 3.2.2.10
• Google Scholar references for 3.2.2.10
• Imada A (1967). "Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. II. Pyrimidine 5'-nucleotide phosphoribo(deoxyribo) hydrolase of Streptomyces virginiae". J. Gen. Appl. Microbiol. 13: 267–278. doi:10.2323/jgam.13.267. 
• Imada A, Kuno M and Igarasi S (1967). "Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. I. Ribose-5-phosphate formation from pyrimidine nucleotides". J. Gen. Appl. Microbiol. 13: 255–265. 

[edit] External links

The CAS registry number for this enzyme class is 9023-31-8.

• IUBMB entry for 3.2.2.10

• KEGG entry for 3.2.2.10

• BRENDA entry for 3.2.2.10

• NiceZyme view of 3.2.2.10

• EC2PDB: PDB structures for 3.2.2.10

• PRIAM entry for 3.2.2.10

• PUMA2 entry for 3.2.2.10

• IntEnz: Integrated Enzyme entry for 3.2.2.10

• MetaCyc entry for 3.2.2.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047405: pyrimidine-5'-nucleotide nucleosidase

• AMIGO entry for GO code 0047405: pyrimidine-5'-nucleotide nucleosidase