Pyridoxine 4-oxidase

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In enzymology, a pyridoxine 4-oxidase (EC 1.1.3.12) is an enzyme that catalyzes the chemical reaction

pyridoxine + O₂ pyridoxal + H₂O₂

Thus, the two substrates of this enzyme are pyridoxine and O₂, whereas its two products are pyridoxal and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyridoxine:oxygen 4-oxidoreductase. Other names in common use include pyridoxin 4-oxidase, and pyridoxol 4-oxidase. This enzyme participates in vitamin b6 metabolism. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.1.3.12
• BRENDA references for 1.1.3.12 (Recommended.)
• PubMed references for 1.1.3.12
• PubMed Central references for 1.1.3.12
• Google Scholar references for 1.1.3.12
• Sundaram TK, Snell EE (1969). "The bacterial oxidation of vitamin B6. V. The enzymatic formation of pyridoxal and isopyridoxal from pyridoxine". J. Biol. Chem. 244: 2577–84. PMID 5769992. 

[edit] External links

The CAS registry number for this enzyme class is 37250-82-1.

• IUBMB entry for 1.1.3.12

• KEGG entry for 1.1.3.12

• BRENDA entry for 1.1.3.12

• NiceZyme view of 1.1.3.12

• EC2PDB: PDB structures for 1.1.3.12

• PRIAM entry for 1.1.3.12

• PUMA2 entry for 1.1.3.12

• IntEnz: Integrated Enzyme entry for 1.1.3.12

• MetaCyc entry for 1.1.3.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050237: pyridoxine 4-oxidase

• AMIGO entry for GO code 0050237: pyridoxine 4-oxidase