Pyridoxamine-phosphate transaminase

From Wikipedia, the free encyclopedia

In enzymology, a pyridoxamine-phosphate transaminase (EC 2.6.1.54) is an enzyme that catalyzes the chemical reaction

pyridoxamine 5'-phosphate + 2-oxoglutarate pyridoxal 5'-phosphate + D-glutamate

Thus, the two substrates of this enzyme are pyridoxamine 5'-phosphate and 2-oxoglutarate, whereas its two products are pyridoxal 5'-phosphate and D-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming). Other names in common use include pyridoxamine phosphate aminotransferase, pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase, and pyridoxamine 5'-phosphate transaminase. This enzyme participates in vitamin b6 metabolism.

[edit] References

• IUBMB entry for 2.6.1.54
• BRENDA references for 2.6.1.54 (Recommended.)
• PubMed references for 2.6.1.54
• PubMed Central references for 2.6.1.54
• Google Scholar references for 2.6.1.54
• Tani Y, Ukita M and Ogata K (1972). "Studies on vitamin B6 metabolism in microorganisms. Part X. Further purification and characterization of pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase from Clostridium kainantoi". Agric. Biol. Chem. 36: 181–188. 

[edit] External links

The CAS registry number for this enzyme class is 9074-84-4.

• IUBMB entry for 2.6.1.54

• KEGG entry for 2.6.1.54

• BRENDA entry for 2.6.1.54

• NiceZyme view of 2.6.1.54

• EC2PDB: PDB structures for 2.6.1.54

• PRIAM entry for 2.6.1.54

• PUMA2 entry for 2.6.1.54

• IntEnz: Integrated Enzyme entry for 2.6.1.54

• MetaCyc entry for 2.6.1.54

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0019163: pyridoxamine-phosphate transaminase

• AMIGO entry for GO code 0019163: pyridoxamine-phosphate transaminase