Pyridoxal oxidase

From Wikipedia, the free encyclopedia

In enzymology, a pyridoxal oxidase (EC 1.2.3.8) is an enzyme that catalyzes the chemical reaction

pyridoxal + H₂O + O₂ 4-pyridoxate + (?)

The 3 substrates of this enzyme are pyridoxal, H₂O, and O₂, whereas its product is 4-pyridoxate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyridoxal:oxygen 4-oxidoreductase. This enzyme participates in vitamin b6 metabolism. It employs one cofactor, molybdenum.

[edit] References

• IUBMB entry for 1.2.3.8
• BRENDA references for 1.2.3.8 (Recommended.)
• PubMed references for 1.2.3.8
• PubMed Central references for 1.2.3.8
• Google Scholar references for 1.2.3.8
• Hanly EW (1980). "Preliminary characterization and physical properties of pyridoxal oxidase activity from Drosophila melanogaster". Mol. Gen. Genet. 180: 455–462. 
• Warner CK, Watts DT and Finnerty V (1980). "Molybdenum hydroxylases in Drosophila. I. Preliminary studies of pyridoxal oxidase". Mol. Gen. Genet. 180: 449–453. 

[edit] External links

The CAS registry number for this enzyme class is 76415-81-1.

• IUBMB entry for 1.2.3.8

• KEGG entry for 1.2.3.8

• BRENDA entry for 1.2.3.8

• NiceZyme view of 1.2.3.8

• EC2PDB: PDB structures for 1.2.3.8

• PRIAM entry for 1.2.3.8

• PUMA2 entry for 1.2.3.8

• IntEnz: Integrated Enzyme entry for 1.2.3.8

• MetaCyc entry for 1.2.3.8

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004732: pyridoxal oxidase

• AMIGO entry for GO code 0004732: pyridoxal oxidase