Pyranose oxidase

From Wikipedia, the free encyclopedia

In enzymology, a pyranose oxidase (EC 1.1.3.10) is an enzyme that catalyzes the chemical reaction

D-glucose + O₂ 2-dehydro-D-glucose + H₂O₂

Thus, the two substrates of this enzyme are D-glucose and O₂, whereas its two products are 2-dehydro-D-glucose and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyranose:oxygen 2-oxidoreductase. Other names in common use include glucose 2-oxidase, and pyranose-2-oxidase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1TT0, 1TZL, 2F5V, 2F6C, 2IGK, 2IGM, 2IGN, and 2IGO.

[edit] References

• IUBMB entry for 1.1.3.10
• BRENDA references for 1.1.3.10 (Recommended.)
• PubMed references for 1.1.3.10
• PubMed Central references for 1.1.3.10
• Google Scholar references for 1.1.3.10
• Janssen FW, Ruelius HW (1968). "Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. II Specificity and characterization of reaction products". Biochim. Biophys. Acta. 167: 501–10. PMID 5722278. 
• Machida Y and Nakanishi T (1984). "Purification and properties of pyranose oxidase from Coriolus versicolor". Agric. Biol. Chem. 48: 2463–2470. 
• Neidleman SL, Amon WF, Jr and Geigert J (1981). "Process for the production of fructose". Chem. Abstr. 94: 20737. 
• Ruelius HW, Kerwin RM, Janssen FW (1968). "Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. I Isolation and purification". Biochim. Biophys. Acta. 167: 493–500. PMID 5725162. 

[edit] External links

The CAS registry number for this enzyme class is 37250-80-9.

• IUBMB entry for 1.1.3.10

• KEGG entry for 1.1.3.10

• BRENDA entry for 1.1.3.10

• NiceZyme view of 1.1.3.10

• EC2PDB: PDB structures for 1.1.3.10

• PRIAM entry for 1.1.3.10

• PUMA2 entry for 1.1.3.10

• IntEnz: Integrated Enzyme entry for 1.1.3.10

• MetaCyc entry for 1.1.3.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050233: pyranose oxidase

• AMIGO entry for GO code 0050233: pyranose oxidase