PXDN

From Wikipedia, the free encyclopedia

Peroxidasin homolog (Drosophila)

Identifiers

PXDN; PRG2; PXN; D2S448; D2S448E; KIAA0230; MG50

External IDs

Gene ontology
Molecular Function:	• peroxidase activity • interleukin-1 receptor antagonist activity • protein binding • metal ion binding
Biological Process:	• immune response

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

XM_001127072 (mRNA)
XP_001127072 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 2: 1.61 - 1.73 Mb

n/a

Pubmed search

[1]

n/a

Peroxidasin homolog (Drosophila), also known as PXDN, is a human gene.^[1]

[edit] References

^ Entrez Gene: PXDN peroxidasin homolog (Drosophila).

[edit] Further reading

Weiler SR, Taylor SM, Deans RJ, et al. (1994). "Assignment of a human melanoma associated gene MG50 (D2S448) to chromosome 2p25.3 by fluorescence in situ hybridization.". Genomics 22 (1): 243–4. doi:10.1006/geno.1994.1374. PMID 7959781.
Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321–9, 341–54. PMID 9039502.
Horikoshi N, Cong J, Kley N, Shenk T (1999). "Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene.". Biochem. Biophys. Res. Commun. 261 (3): 864–9. doi:10.1006/bbrc.1999.1123. PMID 10441517.
Mitchell MS, Kan-Mitchell J, Minev B, et al. (2000). "A novel melanoma gene (MG50) encoding the interleukin 1 receptor antagonist and six epitopes recognized by human cytolytic T lymphocytes.". Cancer Res. 60 (22): 6448–56. PMID 11103812.
Xu YC, Wu RF, Gu Y, et al. (2002). "Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase.". J. Biol. Chem. 277 (31): 28051–7. doi:10.1074/jbc.M202665200. PMID 12023963.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.