Putrescine oxidase

From Wikipedia, the free encyclopedia

In enzymology, a putrescine oxidase (EC 1.4.3.10) is an enzyme that catalyzes the chemical reaction

putrescine + O₂ + H₂O 4-aminobutanal + NH₃ + H₂O₂

The 3 substrates of this enzyme are putrescine, O₂, and H₂O, whereas its 3 products are 4-aminobutanal, NH₃, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is putrescine:oxygen oxidoreductase (deaminating). This enzyme participates in urea cycle and metabolism of amino groups. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.4.3.10
• BRENDA references for 1.4.3.10 (Recommended.)
• PubMed references for 1.4.3.10
• PubMed Central references for 1.4.3.10
• Google Scholar references for 1.4.3.10
• DeSa RJ (1972). "Putrescine oxidase from Micrococcus rubens. Purification and properties of the enzyme". J. Biol. Chem. 247: 5527–34. PMID 4341347. 
• Yamada H (1971). "Putrescine oxidase (Micrococcus rubens)". Methods Enzymol. 17B: 726–730. 

[edit] External links

The CAS registry number for this enzyme class is 9076-87-3.

• IUBMB entry for 1.4.3.10

• KEGG entry for 1.4.3.10

• BRENDA entry for 1.4.3.10

• NiceZyme view of 1.4.3.10

• EC2PDB: PDB structures for 1.4.3.10

• PRIAM entry for 1.4.3.10

• PUMA2 entry for 1.4.3.10

• IntEnz: Integrated Enzyme entry for 1.4.3.10

• MetaCyc entry for 1.4.3.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050232: putrescine oxidase

• AMIGO entry for GO code 0050232: putrescine oxidase