PSMD6

From Wikipedia, the free encyclopedia

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 6

Identifiers

PSMD6; S10; KIAA0107; SGA-113M; p44S10

External IDs

MGI: 1913663 HomoloGene: 7157

Gene ontology
Molecular Function:	• ATPase activity
Cellular Component:	• proteasome complex (sensu Eukaryota) • cytosol
Biological Process:	• ATP-dependent proteolysis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014814 (mRNA)
NP_055629 (protein)

NM_025550 (mRNA)
NP_079826 (protein)

Location

Chr 3: 63.97 - 63.98 Mb

Chr 14: 12.91 - 12.91 Mb

Pubmed search

[1]

[2]

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 6, also known as PSMD6, is a human gene.^[1]

[edit] References

^ Entrez Gene: PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6.

[edit] Further reading

Goff SP (2003). "Death by deamination: a novel host restriction system for HIV-1.". Cell 114 (3): 281–3. PMID 12914693.
Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 2 (1): 37–43. PMID 7788527.
Seeger M, Ferrell K, Frank R, Dubiel W (1997). "HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation.". J. Biol. Chem. 272 (13): 8145–8. PMID 9079628.
Madani N, Kabat D (1998). "An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein.". J. Virol. 72 (12): 10251–5. PMID 9811770.
Simon JH, Gaddis NC, Fouchier RA, Malim MH (1998). "Evidence for a newly discovered cellular anti-HIV-1 phenotype.". Nat. Med. 4 (12): 1397–400. doi:10.1038/3987. PMID 9846577.
Ren S, Smith MJ, Louro ID, et al. (2000). "The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma.". Oncogene 19 (11): 1419–27. doi:10.1038/sj.onc.1203462. PMID 10723133.
Mulder LC, Muesing MA (2000). "Degradation of HIV-1 integrase by the N-end rule pathway.". J. Biol. Chem. 275 (38): 29749–53. doi:10.1074/jbc.M004670200. PMID 10893419.
Sheehy AM, Gaddis NC, Choi JD, Malim MH (2002). "Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein.". Nature 418 (6898): 646–50. doi:10.1038/nature00939. PMID 12167863.
Huang X, Seifert U, Salzmann U, et al. (2002). "The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.". J. Mol. Biol. 323 (4): 771–82. PMID 12419264.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gaddis NC, Chertova E, Sheehy AM, et al. (2003). "Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions.". J. Virol. 77 (10): 5810–20. PMID 12719574.
Lecossier D, Bouchonnet F, Clavel F, Hance AJ (2003). "Hypermutation of HIV-1 DNA in the absence of the Vif protein.". Science 300 (5622): 1112. doi:10.1126/science.1083338. PMID 12750511.
Zhang H, Yang B, Pomerantz RJ, et al. (2003). "The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA.". Nature 424 (6944): 94–8. doi:10.1038/nature01707. PMID 12808465.
Mangeat B, Turelli P, Caron G, et al. (2003). "Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.". Nature 424 (6944): 99–103. doi:10.1038/nature01709. PMID 12808466.
Harris RS, Bishop KN, Sheehy AM, et al. (2003). "DNA deamination mediates innate immunity to retroviral infection.". Cell 113 (6): 803–9. PMID 12809610.
Harris RS, Sheehy AM, Craig HM, et al. (2003). "DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses.". Nat. Immunol. 4 (7): 641–3. doi:10.1038/ni0703-641. PMID 12830140.
Gu Y, Sundquist WI (2003). "Good to CU.". Nature 424 (6944): 21–2. doi:10.1038/424021a. PMID 12840737.
Mariani R, Chen D, Schröfelbauer B, et al. (2003). "Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.". Cell 114 (1): 21–31. PMID 12859895.
KewalRamani VN, Coffin JM (2003). "Virology. Weapons of mutational destruction.". Science 301 (5635): 923–5. doi:10.1126/science.1088965. PMID 12920286.