From Wikipedia, the free encyclopedia
Log page index: User:ProteinBoxBot/PBB_Log_Index
[edit] Protein Status Quick Log - Date: 17:50, 21 January 2008 (UTC)
[edit] Proteins without matches (1)
[edit] Redirected Proteins (24)
[edit] Created (22)
[edit] Manual Inspection (Page not found) (1)
[edit] Updated (2)
[edit] Protein Status Grid - Date: 17:50, 21 January 2008 (UTC)
[edit] Vebose Log - Date: 17:50, 21 January 2008 (UTC)
- INFO: Beginning work on ADAM11... {January 21, 2008 9:43:53 AM PST}
- REDIRECT: Protein Redirected to: ADAM11 {January 21, 2008 9:44:39 AM PST}
- CREATED: Created new protein page: ADAM11 {January 21, 2008 9:44:48 AM PST}
- INFO: Beginning work on CYP4F3... {January 21, 2008 9:39:41 AM PST}
- REDIRECT: Protein Redirected to: CYP4F3 {January 21, 2008 9:40:30 AM PST}
- CREATED: Created new protein page: CYP4F3 {January 21, 2008 9:40:37 AM PST}
- INFO: Beginning work on GTF2H5... {January 21, 2008 9:52:10 AM PST}
- UPLOAD: Added new Image to wiki: {January 21, 2008 9:52:53 AM PST}
- REDIRECT: Protein Redirected to: GTF2H5 {January 21, 2008 9:53:00 AM PST}
- CREATED: Created new protein page: GTF2H5 {January 21, 2008 9:53:13 AM PST}
- INFO: Beginning work on KIF5C... {January 21, 2008 9:35:18 AM PST}
- UPLOAD: Added new Image to wiki: {January 21, 2008 9:35:55 AM PST}
- REDIRECT: Protein Redirected to: KIF5C {January 21, 2008 9:36:02 AM PST}
- CREATED: Created new protein page: KIF5C {January 21, 2008 9:36:16 AM PST}
- INFO: Beginning work on KIFC3... {January 21, 2008 9:36:16 AM PST}
- UPLOAD: Added new Image to wiki: {January 21, 2008 9:37:01 AM PST}
- REDIRECT: Protein Redirected to: KIFC3 {January 21, 2008 9:37:09 AM PST}
- CREATED: Created new protein page: KIFC3 {January 21, 2008 9:37:15 AM PST}
- INFO: Beginning work on KRT33B... {January 21, 2008 9:37:15 AM PST}
- REDIRECT: Protein Redirected to: KRT33B {January 21, 2008 9:38:08 AM PST}
- CREATED: Created new protein page: KRT33B {January 21, 2008 9:38:14 AM PST}
- INFO: Beginning work on LGALS4... {January 21, 2008 9:38:14 AM PST}
- UPLOAD: Added new Image to wiki: {January 21, 2008 9:38:46 AM PST}
- REDIRECT: Protein Redirected to: LGALS4 {January 21, 2008 9:38:53 AM PST}
- CREATED: Created new protein page: LGALS4 {January 21, 2008 9:38:59 AM PST}
- INFO: Beginning work on LHX1... {January 21, 2008 9:38:59 AM PST}
- REDIRECT: Protein Redirected to: LHX1 {January 21, 2008 9:39:34 AM PST}
- CREATED: Created new protein page: LHX1 {January 21, 2008 9:39:41 AM PST}
- INFO: Beginning work on MAFA... {January 21, 2008 9:51:12 AM PST}
- REDIRECT: Protein Redirected to: MAFA (gene) {January 21, 2008 9:51:54 AM PST}
- CREATED: Created new protein page: MAFA (gene) {January 21, 2008 9:52:10 AM PST}
- INFO: Beginning work on MAGEA12... {January 21, 2008 9:41:11 AM PST}
- REDIRECT: Protein Redirected to: MAGEA12 {January 21, 2008 9:41:25 AM PST}
- CREATED: Created new protein page: MAGEA12 {January 21, 2008 9:41:32 AM PST}
- INFO: Beginning work on MAGEA3... {January 21, 2008 9:40:37 AM PST}
- REDIRECT: Protein Redirected to: MAGEA3 {January 21, 2008 9:41:04 AM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {January 21, 2008 9:41:06 AM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {January 21, 2008 9:41:06 AM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {January 21, 2008 9:41:06 AM PST}
- UPDATED: Updated protein page: MAGEA3 {January 21, 2008 9:41:11 AM PST}
- INFO: Beginning work on MAN1A1... {January 21, 2008 9:41:32 AM PST}
- UPLOAD: Added new Image to wiki: {January 21, 2008 9:42:33 AM PST}
- REDIRECT: Protein Redirected to: MAN1A1 {January 21, 2008 9:42:40 AM PST}
- CREATED: Created new protein page: MAN1A1 {January 21, 2008 9:42:47 AM PST}
- INFO: Beginning work on MAP3K9... {January 21, 2008 9:47:47 AM PST}
- REDIRECT: Protein Redirected to: MAP3K9 {January 21, 2008 9:48:16 AM PST}
- CREATED: Created new protein page: MAP3K9 {January 21, 2008 9:48:29 AM PST}
- INFO: Beginning work on MATN1... {January 21, 2008 9:42:47 AM PST}
- REDIRECT: Protein Redirected to: MATN1 {January 21, 2008 9:43:38 AM PST}
- CREATED: Created new protein page: MATN1 {January 21, 2008 9:43:53 AM PST}
- INFO: Beginning work on MEOX1... {January 21, 2008 9:44:48 AM PST}
- REDIRECT: Protein Redirected to: MEOX1 {January 21, 2008 9:45:18 AM PST}
- CREATED: Created new protein page: MEOX1 {January 21, 2008 9:45:25 AM PST}
- INFO: Beginning work on METTL1... {January 21, 2008 9:45:25 AM PST}
- REDIRECT: Protein Redirected to: METTL1 {January 21, 2008 9:46:20 AM PST}
- CREATED: Created new protein page: METTL1 {January 21, 2008 9:46:26 AM PST}
- INFO: Beginning work on MGST2... {January 21, 2008 9:46:26 AM PST}
- REDIRECT: Protein Redirected to: MGST2 {January 21, 2008 9:46:42 AM PST}
- CREATED: Created new protein page: MGST2 {January 21, 2008 9:46:48 AM PST}
- INFO: Beginning work on MIRH1... {January 21, 2008 9:53:13 AM PST}
- REDIRECT: Protein Redirected to: MIRH1 {January 21, 2008 9:53:26 AM PST}
- CREATED: Created new protein page: MIRH1 {January 21, 2008 9:53:32 AM PST}
- INFO: Beginning work on MLF1... {January 21, 2008 9:46:48 AM PST}
- REDIRECT: Protein Redirected to: MLF1 {January 21, 2008 9:47:41 AM PST}
- CREATED: Created new protein page: MLF1 {January 21, 2008 9:47:47 AM PST}
- INFO: Beginning work on MN1... {January 21, 2008 9:48:29 AM PST}
- REDIRECT: Page directory gave bad page (MN1 (gene)). Continuing with search.. Please correct entry: <4330,MN1 (gene)>. {January 21, 2008 9:48:42 AM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {January 21, 2008 9:48:52 AM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Meningioma (disrupted in balanced translocation) 1
| HGNCid = 7180
| Symbol = MN1
| AltSymbols =; MGCR; MGCR1; MGCR1-PEN; dJ353E16.2
| OMIM = 156100
| ECnumber =
| Homologene = 37620
| MGIid = 1261813
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}}
| Process = {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0008150 |text = biological_process}} {{GNF_GO|id=GO:0045786 |text = negative regulation of progression through cell cycle}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 4330
| Hs_Ensembl =
| Hs_RefseqProtein = NP_002421
| Hs_RefseqmRNA = NM_002430
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene = 433938
| Mm_Ensembl = ENSMUSG00000070576
| Mm_RefseqmRNA = XM_485667
| Mm_RefseqProtein = XP_485667
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 5
| Mm_GenLoc_start = 111658469
| Mm_GenLoc_end = 111695094
| Mm_Uniprot =
}}
}}
'''Meningioma (disrupted in balanced translocation) 1''', also known as '''MN1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MN1 meningioma (disrupted in balanced translocation) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4330| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.<ref name="entrez">{{cite web | title = Entrez Gene: MN1 meningioma (disrupted in balanced translocation) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4330| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Grosveld GC |title=MN1, a novel player in human AML. |journal=Blood Cells Mol. Dis. |volume=39 |issue= 3 |pages= 336-9 |year= 2007 |pmid= 17698380 |doi= 10.1016/j.bcmd.2007.06.009 }}
*{{cite journal | author=Buijs A, Sherr S, van Baal S, ''et al.'' |title=Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. |journal=Oncogene |volume=10 |issue= 8 |pages= 1511-9 |year= 1995 |pmid= 7731705 |doi= }}
*{{cite journal | author=Lekanne Deprez RH, Riegman PH, Groen NA, ''et al.'' |title=Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma. |journal=Oncogene |volume=10 |issue= 8 |pages= 1521-8 |year= 1995 |pmid= 7731706 |doi= }}
*{{cite journal | author=Gastier JM, Brody T, Pulido JC, ''et al.'' |title=Development of a screening set for new (CAG/CTG)n dynamic mutations. |journal=Genomics |volume=32 |issue= 1 |pages= 75-85 |year= 1996 |pmid= 8786123 |doi= 10.1006/geno.1996.0078 }}
*{{cite journal | author=van Wely KH, Molijn AC, Buijs A, ''et al.'' |title=The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription. |journal=Oncogene |volume=22 |issue= 5 |pages= 699-709 |year= 2003 |pmid= 12569362 |doi= 10.1038/sj.onc.1206124 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal | author=Sutton AL, Zhang X, Ellison TI, Macdonald PN |title=The 1,25(OH)2D3-regulated transcription factor MN1 stimulates vitamin D receptor-mediated transcription and inhibits osteoblastic cell proliferation. |journal=Mol. Endocrinol. |volume=19 |issue= 9 |pages= 2234-44 |year= 2005 |pmid= 15890672 |doi= 10.1210/me.2005-0081 }}
*{{cite journal | author=Kawagoe H, Grosveld GC |title=MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice. |journal=Blood |volume=106 |issue= 13 |pages= 4278-86 |year= 2006 |pmid= 16081688 |doi= 10.1182/blood-2005-04-1674 }}
*{{cite journal | author=Kawagoe H, Grosveld GC |title=Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9. |journal=Blood |volume=106 |issue= 13 |pages= 4269-77 |year= 2006 |pmid= 16105979 |doi= 10.1182/blood-2005-04-1679 }}
*{{cite journal | author=Meester-Smoor MA, Molijn AC, Zhao Y, ''et al.'' |title=The MN1 oncoprotein activates transcription of the IGFBP5 promoter through a CACCC-rich consensus sequence. |journal=J. Mol. Endocrinol. |volume=38 |issue= 1-2 |pages= 113-25 |year= 2007 |pmid= 17242174 |doi= 10.1677/jme.1.02110 }}
*{{cite journal | author=Heuser M, Argiropoulos B, Kuchenbauer F, ''et al.'' |title=MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. |journal=Blood |volume=110 |issue= 5 |pages= 1639-47 |year= 2007 |pmid= 17494859 |doi= 10.1182/blood-2007-03-080523 }}
*{{cite journal | author=Carella C, Bonten J, Sirma S, ''et al.'' |title=MN1 overexpression is an important step in the development of inv(16) AML. |journal=Leukemia |volume=21 |issue= 8 |pages= 1679-90 |year= 2007 |pmid= 17525718 |doi= 10.1038/sj.leu.2404778 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on MPP2... {January 21, 2008 9:48:52 AM PST}
- REDIRECT: Protein Redirected to: MPP2 {January 21, 2008 9:49:44 AM PST}
- CREATED: Created new protein page: MPP2 {January 21, 2008 9:49:49 AM PST}
- INFO: Beginning work on NHLRC1... {January 21, 2008 9:50:11 AM PST}
- REDIRECT: Protein Redirected to: NHLRC1 {January 21, 2008 9:50:44 AM PST}
- CREATED: Created new protein page: NHLRC1 {January 21, 2008 9:50:52 AM PST}
- INFO: Beginning work on NOMO1... {January 21, 2008 9:49:49 AM PST}
- REDIRECT: Protein Redirected to: NOMO1 {January 21, 2008 9:50:03 AM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {January 21, 2008 9:50:05 AM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {January 21, 2008 9:50:05 AM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {January 21, 2008 9:50:05 AM PST}
- UPDATED: Updated protein page: NOMO1 {January 21, 2008 9:50:11 AM PST}
- INFO: Beginning work on TNFSF12-TNFSF13... {January 21, 2008 9:53:32 AM PST}
- REDIRECT: Protein Redirected to: TNFSF12-TNFSF13 {January 21, 2008 9:53:52 AM PST}
- CREATED: Created new protein page: TNFSF12-TNFSF13 {January 21, 2008 9:53:58 AM PST}
- INFO: Beginning work on ZFP91-CNTF... {January 21, 2008 9:50:52 AM PST}
- REDIRECT: Protein Redirected to: ZFP91-CNTF {January 21, 2008 9:51:06 AM PST}
- CREATED: Created new protein page: ZFP91-CNTF {January 21, 2008 9:51:12 AM PST}
end log.