Talk:Proline
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Article Grading: The following comments were left by the quality and importance raters: (edit · refresh) Please I recently learnt that L-Proline is converted to D-Proline which is a known toxin that attacks human internal organs and nervous system. (Lancet Dec. 9th 1989)Please are there other sources for further reading on this topic? Milko Johnson217.43.176.54 (talk) 16:53, 6 January 2008 (UTC) |
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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) Please I recently learnt that L-Proline is converted to D-Proline which is a known toxin that attacks human internal organs and nervous system. (Lancet Dec. 9th 1989)Please are there other sources for further reading on this topic? Milko Johnson217.43.176.54 (talk) 16:53, 6 January 2008 (UTC) |
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[edit] Imino acid
Why isn't proline an imino acid?
It is... Technichally proteins in the human body are made from 19 typical amino acids and one typical imino acid along with some other infrequently used amino acids. 132.162.240.58
We should probably correct the article to show that then. According to "Molecular Biology of the Cell, 4th edition" by Alberts et al., page 133, proline is indeed an imino acid.Canadian popcan 04:20, 3 October 2005 (UTC)
According to the IUPAC, Proline IS NOT an Imino Acid or an Amino Acid. It's an azaalkanoic acid. I've modified the article to reflect that.
http://www.iupac.org/goldbook/I02959.pdf Morwan
Proline is an amino aicd. I.e. it is an amine and it is an acid. It is a secondary amine and it is cyclic, but it is stil an amine - NOT and imine. IUPAC accepts the use of the term "amino acid" and thus it is not necessary to use the (quite uncommon) word "azaalkanoic aicd." 130.225.102.1 (talk) 10:42, 7 January 2008 (UTC)
[edit] Energy drinks
The article currently includes a rather non-encyclopedic blurb about how for some unknown reason, Proline is included as an ingredient in some energy drinks. I am curious about this (as I chug down my Sobe fruit punch)... can anyone add any information to that, to make it more informative? --Norville 14:08, 14 March 2007 (UTC)
Whats really weird about the energy drink citation is that last I checked, you ought not need to look any further than the ingredient label to prove such a thing. Perhaps the person who included the blurb was confused by why proline is in an energy drink in the first place? My feeling, and it is only a feeling, is that a likely explanation is located right above the blurb in question: proline has a flavor! Zaphraud 19:50, 12 July 2007 (UTC)
In bacteria, proline can enter the Krebb's cycle and provide a secondary energy source by first being converted to glutamate. In animals, the availability of proline to the Krebb's cycle is restricted by slow transport across the mitochondrial membrane. So, although Sobe thinks they are providing an energy source, it would only be so if you were a bacteria. Kevin.stafford 16:53, 17 April 2007 (UTC)kevin.stafford April 2007
[edit] Understanding
I am a graduate student of biochemistry, and even I had trouble understanding some of the statements regarding proline - particularly the last section before the energy drink blurb. I imagine that an average Wikipedia reader would not be able to understand much beyond the intro and the trivia at the end. While I am glad to see a wealth of information here, it should be at least somewhat accessible to a reader who has only cursory knowledge of biochemistry and proteins. I reworded a few sentences, added links, and added an explanation for the "X" that comes out of nowhere in the cis-trans section, but someone with more knowledge/skills could improve it further. I think this is one of the better amino acid articles, and I'd like to see it become even better. GngstrMNKY (talk) 21:52, 2 February 2008 (UTC)
[edit] Why external link have been removed?
Dear Dirk Beetstra, I would be very grateful if you could explain why you removed external link http://www.peptideguide.com/amino-acids/proline.html ? Is the following page http://www.compchemwiki.org/index.php?title=Proline more relevant than my link?
Thanks in advance! —Preceding unsigned comment added by 217.150.28.145 (talk) 14:54, 11 March 2008 (UTC)
