Protein-serine epimerase

From Wikipedia, the free encyclopedia

In enzymology, a protein-serine epimerase (EC 5.1.1.16) is an enzyme that catalyzes the chemical reaction

[protein]-L-serine [protein]-D-serine

Hence, this enzyme has one substrate, [[[protein]-L-serine]], and one product, [[[protein]-D-serine]].

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is [protein]-serine epimerase. This enzyme is also called protein-serine racemase.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1WTC.

[edit] References

• IUBMB entry for 5.1.1.16
• BRENDA references for 5.1.1.16 (Recommended.)
• PubMed references for 5.1.1.16
• PubMed Central references for 5.1.1.16
• Google Scholar references for 5.1.1.16
• Katayama K, Kuwada M (1995). "Isolation and characterization of a peptide isomerase from funnel web spider venom". J. Biol. Chem. 270: 16719–23. doi:10.1074/jbc.270.28.16719. PMID 7622482. 

[edit] External links

The CAS registry number for this enzyme class is 169592-52-3.

• IUBMB entry for 5.1.1.16

• KEGG entry for 5.1.1.16

• BRENDA entry for 5.1.1.16

• NiceZyme view of 5.1.1.16

• EC2PDB: PDB structures for 5.1.1.16

• PRIAM entry for 5.1.1.16

• PUMA2 entry for 5.1.1.16

• IntEnz: Integrated Enzyme entry for 5.1.1.16

• MetaCyc entry for 5.1.1.16

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018365: protein-serine epimerase

• AMIGO entry for GO code 0018365: protein-serine epimerase