Protein-secreting ATPase

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In enzymology, a protein-secreting ATPase (EC 3.6.3.50) is an enzyme that catalyzes the chemical reaction

ATP + H₂O $\rightleftharpoons$ ADP + phosphate

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (protein-secreting).

1 References
2 See also
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] References

IUBMB entry for 3.6.3.50
BRENDA references for 3.6.3.50 (Recommended.)
PubMed references for 3.6.3.50
PubMed Central references for 3.6.3.50
Google Scholar references for 3.6.3.50
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Martinez A, Ostrovsky P, Nunn DN (1998). "Identification of an additional member of the secretin superfamily of proteins in Pseudomonas aeruginosa that is able to function in type II protein secretion". Mol. Microbiol. 28: 1235–46. PMID 9680212.
Schuch R, Maurelli AT (1999). "The mxi-Spa type III secretory pathway of Shigella flexneri requires an outer membrane lipoprotein, MxiM, for invasin translocation". Infect. Immun. 67: 1982–91. PMID 10085046.