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Protease-sparing regimen often abbreviated as PSR, is a method or therapy for treating people infected with HIV that involves a three-drug combination that reduces viral load below the limit of detection while saving protease inhibitors for later use. It is considered a weaker (in terms of quantity and concentration) form of HIV treatment. It has been argued that such a regimen is not as potent as giving HIV patients with the strongest drugs as soon as it is detected. Others believe that this might be considered a long-term strategy in order to reduce the amount of HIV[1], and in some instances have proven to be successful[2]
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