Prostaglandin E synthase

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prostaglandin E synthase
Identifiers
Symbol	PTGES
Alt. Symbols	MGST1L1
Entrez	9536
HUGO	9599
OMIM	605172
RefSeq	NM_004878
UniProt	O14684
Other data
Locus	Chr. 9 q34.3

prostaglandin E synthase 2
Identifiers
Symbol	PTGES2
Alt. Symbols	C9orf15
Entrez	80142
HUGO	17822
OMIM	608152
RefSeq	NM_198939
UniProt	Q9H7Z7
Other data
Locus	Chr. 9 q34.12

prostaglandin E synthase 3 (cytosolic)
Identifiers
Symbol	PTGES3
Entrez	10728
HUGO	16049
OMIM	607061
RefSeq	NM_006601
UniProt	Q15185
Other data
Locus	Chr. 12 q13.13

Prostaglandin E synthase (or PGE synthase) is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E (PGE) from prostaglandin H2.

The synthase generating PGE2 is a membrane-associated protein also known as mPEGS-1^[1].

[edit] References

1. ^ op.se (Swedish)

[edit] External links

• MeSH prostaglandin-E+synthase
• EC 5.3.99.3

v • d • e Intramolecular oxidoreductases isomerases (EC 5.3) 5.3.1 - Aldoses/Ketoses Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase 5.3.3 - C=C Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase 5.3.4 - S-S Protein disulfide isomerase (PDIA3) 5.3.99 - other Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase

v • d • e Metabolism: lipid metabolism - eicosanoid metabolism enzymes Prostanoids Cyclooxygenase - Thromboxane-A synthase - Prostacyclin synthase - Prostaglandin E synthase - Prostaglandin D2 synthase Leukotrienes Arachidonate 5-lipoxygenase - 5-Lipoxygenase activating protein - Leukotriene A4 hydrolase - Leukotriene C4 synthase