Prostaglandin-A1 Delta-isomerase

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In enzymology, a prostaglandin-A1 Delta-isomerase (EC 5.3.3.9) is an enzyme that catalyzes the chemical reaction

(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate

Hence, this enzyme has one substrate, (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate, and one product, (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate Delta10-Delta11-isomerase. This enzyme is also called prostaglandin A isomerase.

[edit] References

• IUBMB entry for 5.3.3.9
• BRENDA references for 5.3.3.9 (Recommended.)
• PubMed references for 5.3.3.9
• PubMed Central references for 5.3.3.9
• Google Scholar references for 5.3.3.9
• Polet H, Levine L (1975). "Metabolism of prostaglandins E, A, and C in serum". J. Biol. Chem. 250: 351–7. PMID 234423. 

[edit] External links

The CAS registry number for this enzyme class is 9055-01-0.

• IUBMB entry for 5.3.3.9

• KEGG entry for 5.3.3.9

• BRENDA entry for 5.3.3.9

• NiceZyme view of 5.3.3.9

• EC2PDB: PDB structures for 5.3.3.9

• PRIAM entry for 5.3.3.9

• PUMA2 entry for 5.3.3.9

• IntEnz: Integrated Enzyme entry for 5.3.3.9

• MetaCyc entry for 5.3.3.9

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050219: prostaglandin-A1 delta-isomerase

• AMIGO entry for GO code 0050219: prostaglandin-A1 delta-isomerase