Primary peritoneal cancer

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Primary peritoneal cancer
Classification and external resources
ICD-10 C48.1-C48.2
ICD-9 158
MeSH D010534

Primary peritoneal cancer or carcinoma ("PPCa")[1] is a cancer of the cells lining the peritoneum, or abdominal cavity.

Some studies indicate that 7–20% of initially diagnosed epithelial ovarian cancers could be properly reclassified as primary peritoneal cancers.

Contents

[edit] Causes

Although the precise causes are not known, an link with certain variants of BRCA has been described.[2]

An association with vascular endothelial growth factor has been observed.[3]

[edit] Prognosis and treatment

Prognosis and treatment is the same as for the most common variation of ovarian cancer, which is epithelial ovarian cancer.[4][5]

Elevated albumin levels have been associated with a more favorable prognosis.[6]

[edit] Mesothelioma

The cancer does involve mesothelial cells and can be medically described as mesothelioma; however, this cancer should not be confused with asbestos-related mesothelioma, which requires different treatments and has a much higher mortality rate.

[edit] References

  1. ^ Jaaback KS, Ludeman L, Clayton NL, Hirschowitz L (2006). "Primary peritoneal carcinoma in a UK cancer center: comparison with advanced ovarian carcinoma over a 5-year period". Int. J. Gynecol. Cancer 16 Suppl 1: 123–8. doi:10.1111/j.1525-1438.2006.00474.x. PMID 16515579. 
  2. ^ Gynecologic Cancer Treatment – Primary Peritoneal Cancer - Dana-Farber Cancer Institute.
  3. ^ Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI (November 2007). "Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study". J. Clin. Oncol. 25 (33): 5165–71. doi:10.1200/JCO.2007.11.5345. PMID 18024863. 
  4. ^ New Drug Combination for Ovarian and Primary Peritoneal Cancers - National Cancer Institute.
  5. ^ eMedicine - Peritoneal Cancer : Article by Wissam Bleibel.
  6. ^ Alphs HH, Zahurak ML, Bristow RE, Díaz-Montes TP (December 2006). "Predictors of surgical outcome and survival among elderly women diagnosed with ovarian and primary peritoneal cancer". Gynecol. Oncol. 103 (3): 1048–53. doi:10.1016/j.ygyno.2006.06.019. PMID 16876237. 

[edit] External links

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