Prephenic acid
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Prephenic acid | |
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Identifiers | |
CAS number | [126-49-8] |
PubChem | |
MeSH | |
SMILES | C1=CC(C=CC1O)(CC(=O)C(=O)O)C(=O)O |
Properties | |
Molecular formula | C10H10O6 |
Molar mass | 226.183 |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Prephenic acid, more commonly known by its anionic form prephenate, is an intermediate in the biosynthesis of the aromatic amino acids phenylalanine and tyrosine.
It is synthesized by a [3,3]-sigmatropic Claisen rearrangement of chorismate.[1][2]
[edit] References
- ^ Helmut Goerisch (1978). "On the mechanism of the chorismate mutase reaction". Biochemistry: 3700. doi: .
- ^ Peter Kast, Yadu B. Tewari, Olaf Wiest, Donald Hilvert, Kendall N. Houk, and Robert N. Goldberg (1997). "Thermodynamics of the Conversion of Chorismate to Prephenate: Experimental Results and Theoretical Predictions". J. Phys. Chem. B 101 (50): 10976–10982. doi: .