PREPL

From Wikipedia, the free encyclopedia


Prolyl endopeptidase-like
Identifiers
Symbol(s) PREPL; FLJ16627; KIAA0436
External IDs OMIM: 609557 MGI: 2441932 HomoloGene: 15481
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9581 213760
Ensembl ENSG00000138078 ENSMUSG00000024127
Refseq NM_001042385 (mRNA)
NP_001035844 (protein)		 NM_145984 (mRNA)
NP_666096 (protein)
Location Chr 2: 44.4 - 44.44 Mb Chr 17: 84.97 - 85 Mb
Pubmed search [1] [2]

Prolyl endopeptidase-like, also known as PREPL, is a human gene.[1]

PREPL belongs to the prolyloligopeptidase subfamily of serine peptidases (Parvari et al., 2005).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: PREPL prolyl endopeptidase-like.

[edit] Further reading

  • Martens K, Derua R, Meulemans S, et al. (2006). "PREPL: a putative novel oligopeptidase propelled into the limelight.". Biol. Chem. 387 (7): 879-83. doi:10.1515/BC.2006.111. PMID 16913837. 
  • Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1995). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.". Genomics 23 (1): 42-50. doi:10.1006/geno.1994.1457. PMID 7829101. 
  • Ishikawa K, Nagase T, Nakajima D, et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 4 (5): 307-13. PMID 9455477. 
  • Parvari R, Brodyansky I, Elpeleg O, et al. (2001). "A recessive contiguous gene deletion of chromosome 2p16 associated with cystinuria and a mitochondrial disease.". Am. J. Hum. Genet. 69 (4): 869-75. PMID 11524703. 
  • Kim DK, Kanai Y, Choi HW, et al. (2002). "Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells.". Biochim. Biophys. Acta 1565 (1): 112-21. PMID 12225859. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Parvari R, Gonen Y, Alshafee I, et al. (2005). "The 2p21 deletion syndrome: characterization of the transcription content.". Genomics 86 (2): 195-211. doi:10.1016/j.ygeno.2005.04.001. PMID 15913950. 
  • Szeltner Z, Alshafee I, Juhász T, et al. (2005). "The PREPL A protein, a new member of the prolyl oligopeptidase family, lacking catalytic activity.". Cell. Mol. Life Sci. 62 (19-20): 2376-81. doi:10.1007/s00018-005-5262-5. PMID 16143824. 
  • Jaeken J, Martens K, Francois I, et al. (2006). "Deletion of PREPL, a gene encoding a putative serine oligopeptidase, in patients with hypotonia-cystinuria syndrome.". Am. J. Hum. Genet. 78 (1): 38-51. doi:10.1086/498852. PMID 16385448. 
 This article on a gene on chromosome 2 is a stub. You can help Wikipedia by expanding it.