Pramocaine

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Pramocaine
Systematic (IUPAC) name
4-[3-(4-butoxyphenoxy)propyl]morpholine
Identifiers
CAS number	140-65-8 637-58-1 (hydrochloride)
ATC code	D04AB07 C05AD07
PubChem	4886
Chemical data
Formula	C17H27NO3
Mol. mass	293.401 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	POM(UK) ℞-only(US) (with hydrocortisone)
Routes	Topical, rectal

Pramocaine (INN and BAN, also known as pramoxine) is a topical anesthetic used as an antipruritic.

Popular itch cream Gold Bond uses pramocaine hydrochloride (hydrochloride used to ease absorption in the skin) to numb sensitive skin.

[edit] Usage

Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches.^[1]Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.

[edit] Notes

[edit] See also

• Local anesthesia

v • d • e Vasoprotectives (C05) Antihemorrhoidals for topical use corticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) - local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) - other (Tribenoside) Antivaricose therapy heparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) other (Calcium dobesilate) Capillary stabilising agents bioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside)

v • d • e Antipruritics (D04) Antihistamines for topical use Thonzylamine - Mepyramine - Thenalidine - Tripelennamine - Chloropyramine - Promethazine - Tolpropamine - Dimetindene - Clemastine - Bamipine - Isothipendyl - Diphenhydramine - Chlorphenoxamine Anesthetics for topical use Lidocaine - Cinchocaine - Oxybuprocaine - Benzocaine - Quinisocaine - Tetracaine - Pramocaine