POSTN
From Wikipedia, the free encyclopedia
Periostin, osteoblast specific factor
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Identifiers | ||||||||||||||
Symbol(s) | POSTN; MGC119510; MGC119511; OSF-2; PDLPOSTN; PN; RP11-412K4.1; periostin | |||||||||||||
External IDs | OMIM: 608777 MGI: 1926321 HomoloGene: 4730 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 10631 | 50706 | ||||||||||||
Ensembl | ENSG00000133110 | ENSMUSG00000027750 | ||||||||||||
Uniprot | Q15063 | Q6GUA3 | ||||||||||||
Refseq | NM_006475 (mRNA) NP_006466 (protein) |
NM_015784 (mRNA) NP_056599 (protein) |
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Location | Chr 13: 37.03 - 37.07 Mb | Chr 3: 54.45 - 54.48 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Periostin, osteoblast specific factor, also known as POSTN, is a human gene.[1]
[edit] References
[edit] Further reading
- Takeshita S, Kikuno R, Tezuka K, Amann E (1993). "Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I.". Biochem. J. 294 ( Pt 1): 271-8. PMID 8363580.
- Sasaki H, Dai M, Auclair D, et al. (2001). "Serum level of the periostin, a homologue of an insect cell adhesion molecule, as a prognostic marker in nonsmall cell lung carcinomas.". Cancer 92 (4): 843-8. PMID 11550156.
- Gillan L, Matei D, Fishman DA, et al. (2002). "Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility.". Cancer Res. 62 (18): 5358-64. PMID 12235007.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi: . PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi: . PMID 14702039.
- Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi: . PMID 15057823.
- Shao R, Bao S, Bai X, et al. (2004). "Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.". Mol. Cell. Biol. 24 (9): 3992-4003. PMID 15082792.
- Bao S, Ouyang G, Bai X, et al. (2004). "Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway.". Cancer Cell 5 (4): 329-39. PMID 15093540.
- Kim CJ, Yoshioka N, Tambe Y, et al. (2005). "Periostin is down-regulated in high grade human bladder cancers and suppresses in vitro cell invasiveness and in vivo metastasis of cancer cells.". Int. J. Cancer 117 (1): 51-8. doi: . PMID 15880581.
- Chang Y, Lee TC, Li JC, et al. (2005). "Differential expression of osteoblast-specific factor 2 and polymeric immunoglobulin receptor genes in nasopharyngeal carcinoma.". Head Neck 27 (10): 873-82. doi: . PMID 16136586.
- Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070-80. doi: . PMID 16335952.
- Yan W, Shao R (2006). "Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation.". J. Biol. Chem. 281 (28): 19700-8. doi: . PMID 16702213.
- Försti A, Jin Q, Altieri A, et al. (2007). "Polymorphisms in the KDR and POSTN genes: association with breast cancer susceptibility and prognosis.". Breast Cancer Res. Treat. 101 (1): 83-93. doi: . PMID 16807673.
- Grigoriadis A, Mackay A, Reis-Filho JS, et al. (2007). "Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.". Breast Cancer Res. 8 (5): R56. doi: . PMID 17014703.
- Baril P, Gangeswaran R, Mahon PC, et al. (2007). "Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway.". Oncogene 26 (14): 2082-94. doi: . PMID 17043657.
- Siriwardena BS, Kudo Y, Ogawa I, et al. (2007). "Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer.". Br. J. Cancer 95 (10): 1396-403. doi: . PMID 17060937.
- Li JS, Sun GW, Wei XY, Tang WH (2007). "Expression of periostin and its clinicopathological relevance in gastric cancer.". World J. Gastroenterol. 13 (39): 5261-6. PMID 17876898.