Pop 100 number-one hits of 2005 (USA)
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These are the number one Pop 100 hits of 2005 per Billboard magazine. The Pop 100 is a chart created in February 2005 by Billboard. It ranks songs based on mainstream Top 40 radio airplay, singles sales, and digital downloads. It is a component chart to the Hot 100 and its airplay points are compiled from electronic monitoring of approximately 115 mainstream Top 40 stations by Nielsen Broadcast Data systems.
| Issue Date | Song | Artist |
| February 12 | "Let Me Love You" | Mario |
| February 19 | "Let Me Love You" | Mario |
| February 26 | "Let Me Love You" | Mario |
| March 5 | "Boulevard of Broken Dreams" | Green Day |
| March 12 | "Boulevard of Broken Dreams" | Green Day |
| March 19 | "Boulevard of Broken Dreams" | Green Day |
| March 26 | "Since U Been Gone" | Kelly Clarkson |
| April 2 | "Since U Been Gone" | Kelly Clarkson |
| April 9 | "Since U Been Gone" | Kelly Clarkson |
| April 16 | "Since U Been Gone" | Kelly Clarkson |
| April 23 | "Since U Been Gone" | Kelly Clarkson |
| April 30 | "Since U Been Gone" | Kelly Clarkson |
| May 7 | "Hollaback Girl" | Gwen Stefani |
| May 14 | "Hollaback Girl" | Gwen Stefani |
| May 21 | "Hollaback Girl" | Gwen Stefani |
| May 28 | "Hollaback Girl" | Gwen Stefani |
| June 4 | "Hollaback Girl" | Gwen Stefani |
| June 11 | "Hollaback Girl" | Gwen Stefani |
| June 18 | "Hollaback Girl" | Gwen Stefani |
| June 25 | "Hollaback Girl" | Gwen Stefani |
| July 2 | "Inside Your Heaven" | Carrie Underwood |
| July 9 | "Inside Your Heaven" | Bo Bice |
| July 16 | "We Belong Together" | Mariah Carey |
| July 23 | "We Belong Together" | Mariah Carey |
| July 30 | "We Belong Together" | Mariah Carey |
| August 6 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| August 13 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| August 20 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| August 27 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| September 3 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| September 10 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| September 17 | "Don't Cha" | The Pussycat Dolls featuring Busta Rhymes |
| September 24 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 1 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 8 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 15 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 22 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 29 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| November 5 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| November 12 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| November 19 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| November 26 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| December 3 | "Run It!" | Chris Brown |
| December 10 | "Run It!" | Chris Brown |
| December 17 | "Run It!" | Chris Brown |
| December 24 | "Run It!" | Chris Brown |
| December 31 | "Run It!" | Chris Brown |
