Polybrene

From Wikipedia, the free encyclopedia

Polybrene (hexadimethrine bromide) is a cationic polymer used to increase the efficiency of infection of certain cells with a retrovirus in cell culture. Polybrene acts by neutralizing the charge repulsion between the virions and cell surface. [1] It has other uses, including a role in protein sequencing.

The chemical name for Polybrene is 1,5-dimethyl-1,5-diazaundecamethylene polymethobromide, hexadimethrine bromide.

[edit] References

  1. ^ Howard E. Davis, Matthew Rosinski , Jeffrey R. Morgan and Martin L. Yarmush, et al (2004). "Charged Polymers Modulate Retrovirus Transduction via Membrane Charge Neutralization and Virus Aggregation.". Biophysical Journal 86: 1234–42. PMID 14747357. 
 This genetics article is a stub. You can help Wikipedia by expanding it.