Poly(3-hydroxyoctanoate) depolymerase

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In enzymology, a poly(3-hydroxyoctanoate) depolymerase (EC 3.1.1.76) is an enzyme that catalyzes the chemical reaction that breaks down the polyester poly{oxycarbonyl[(R)-2-pentylethylene]} into smaller oligomers.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase. Other names in common use include PHO depolymerase, poly(3HO) depolymerase, poly[(R)-hydroxyalkanoic acid] depolymerase, poly(HA) depolymerase, poly(HAMCL) depolymerase, and poly[(R)-3-hydroxyoctanoate] hydrolase.

[edit] References

IUBMB entry for 3.1.1.76
BRENDA references for 3.1.1.76 (Recommended.)
PubMed references for 3.1.1.76
PubMed Central references for 3.1.1.76
Google Scholar references for 3.1.1.76
Jendrossek D (2001). "Microbial degradation of polyesters". Adv. Biochem. Eng. Biotechnol. 71: 293–325. PMID 11217416.
Prieto MA, Garcia JL, Martinez M, Luengo JM (1999). "Novel biodegradable aromatic plastics from a bacterial source Genetic and biochemical studies on a route of the phenylacetyl-coa catabolon". J. Biol. Chem. 274: 29228–41. doi:10.1074/jbc.274.41.29228. PMID 10506180.
Schirmer A, Jendrossek D, Schlegel HG (1993). "Degradation of poly(3-hydroxyoctanoic acid) [P(3HO)] by bacteria: purification and properties of a P(3HO) depolymerase from Pseudomonas fluorescens GK13". Appl. Environ. Microbiol. 59: 1220–7. PMID 8476295.