POLDIP2

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Polymerase (DNA-directed), delta interacting protein 2
Identifiers
Symbol(s) POLDIP2; DKFZP586F1524; PDIP38; POLD4
External IDs MGI: 1915061 HomoloGene: 9201
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 26073 67811
Ensembl ENSG00000004142 ENSMUSG00000001100
Uniprot Q9Y2S7 Q5SYH1
Refseq NM_015584 (mRNA)
NP_056399 (protein)		 NM_026389 (mRNA)
NP_080665 (protein)
Location Chr 17: 23.7 - 23.71 Mb Chr 11: 78.33 - 78.34 Mb
Pubmed search [1] [2]

Polymerase (DNA-directed), delta interacting protein 2, also known as POLDIP2, is a human gene.[1]

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. The encoded protein also interacts with proliferating cell nuclear antigen. Some transcripts of this gene overlap in a tail-to-tail orientation with the gene for tumor necrosis factor, alpha-induced protein 1 (TNFAIP1).[1]

[edit] References

  1. ^ a b Entrez Gene: POLDIP2 polymerase (DNA-directed), delta interacting protein 2.

[edit] Further reading

  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Liu L, Rodriguez-Belmonte EM, Mazloum N, et al. (2003). "Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen.". J. Biol. Chem. 278 (12): 10041–7. doi:10.1074/jbc.M208694200. PMID 12522211. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Xie B, Li H, Wang Q, et al. (2005). "Further characterization of human DNA polymerase delta interacting protein 38.". J. Biol. Chem. 280 (23): 22375–84. doi:10.1074/jbc.M414597200. PMID 15811854. 
  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901. 
  • Klaile E, Müller MM, Kannicht C, et al. (2007). "The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38.". J. Biol. Chem. 282 (36): 26629–40. doi:10.1074/jbc.M701807200. PMID 17623671. 
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