Talk:Pneumococcal conjugate vaccine
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[edit] Evidence supporting addition to routine vaccination schedules
According to one study, doctor visits by those who were diagnosed as having chronic ear infections and who took Prevnar dropped about 20 percent, and there was a similar 20 percent reduction in the number of children who needed tube implants to fight the infections, and overall ear infections were reduced by 9 percent.
For US children under the age of two, the chance of being diagnosed with an invasive pneumococcal disease was determined to be about .15%, or about one chile in 666. Pneumococcal meningitis in childhood has been 'associated with' a mortality rate of approximately 1 in 178,571 children. According to data from the product insert, after one dose of the vaccine .016% of the recipients (3 out of 18,906) were diagnosed with invasive pneumococcal disease; .14% of controls (27 out of 18,910 injected with a different vaccine) got invasive pneumococcal disease. Thus, it was determined Prevnar decreases a child's chance of getting invasive pneumococcal disease by approximately 0.1%.
According to a press release from Wyeth, "...a major clinical trial conducted by Kaiser Permanente.suggested that the vaccine is effective against invasive pneumococcal disease caused by seven serotypes (strains) of the bacteria most prevalent among children in the U.S." According to the Harvard Medical School, the Kaiser study was supported by a grant from Wyeth.
According to the study paid for by Wyeth, "The study showed that children in the vaccine group fared better than those in the comparison group in other ways. In the primary analysis of all acute otitis media episodes (i.e. earaches), children receiving the investigational 7-valent pnemococcal vaccine (i.e. Prevnar) had 7 percent fewer new episodes."
[edit] Key Supporters of Prevnar
Key supporters of adding Prevnar to universal vaccination schedules included:
- Dr. Steven Black, Kaiser Permanente
- Dr. Henry Shinefield, Kaiser Permanente
- Dr. Stephen I. Pelton, Boston Medical Center
- Dr. Jerome Klein, Boston Medical Center
- Dr. Margaret B. Rennels, University of Maryland Medical Center
- Dr. Kathryn M. Edwards, Vanderbilt University School of Medicine
Drs. Black and Shinefield undertook most of the studies on Prevnar which proved its efficacy and safety. In promoting the idea of adding four more injections into an already crowded universal US vaccination schedule, Dr. Black asserted, "This vaccine is urgently needed...It is great news for parents and physicians." Dr. Shinefield has said, "It's a remarkable vaccine that will have a dramatic effect." The two Kaiser doctors have spoken at medical conferences throughout the world promoting Prevnar to their colleagues in the medical industry. "
Midgley 18:22, 22 May 2006 (UTC)
[edit] merge
I suggest there should be one article on pneumococcal vaccines. Prevnar gets a paragraph in it. Midgley 18:28, 22 May 2006 (UTC)
[edit] Proposed move
"Prevnar" should be moved to the generic name of the vaccine: pneumococcal conjugate vaccine. Axl 06:54, 4 September 2007 (UTC)
- Agreed; we generally use generic rather than trade names. Without speculating on why this particular article was started under "Prevnar", we ought to move it and leave Prevnar as a redirect, as Axl suggests. MastCell Talk 14:49, 4 September 2007 (UTC)
Hello- the 1st paragraph should be changed, it uses the commercial name of the 1st conjugate vaccine, however, 10, and 13 valent conjugate vaccines will soon arrive on the market. very important to be balanced and UTD for the credibility of wikipedia. and users of info on this page... —Preceding unsigned comment added by 216.129.222.137 (talk) 16:27, 25 February 2008 (UTC)
[edit] Pneumococcal vaccines
I agree with Midgley's suggestion for merging all pneumococcal vaccines related articles. A general article including available informations about all pneumococcal vaccines is more suitable to cover all the problems regarding the pneumoccocal vaccination (including history of pneumococcal vaccination, suitable vaccines to be used at different ages or in different countries, new perspectives in pneumococcal vaccination and so on). RO BlueMonday (talk) 13:53, 1 April 2008 (UTC)
