PLXND1

From Wikipedia, the free encyclopedia

Plexin D1

Identifiers

PLXND1; KIAA0620; MGC75353; PLEXD1

External IDs

OMIM: 604282 MGI: 2154244 HomoloGene: 22866

Gene ontology
Molecular Function:	• receptor activity • protein binding • semaphorin receptor activity
Cellular Component:	• membrane • integral to membrane
Biological Process:	• patterning of blood vessels • multicellular organismal development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_015103 (mRNA)
NP_055918 (protein)

NM_026376 (mRNA)
NP_080652 (protein)

Location

Chr 3: 130.76 - 130.81 Mb

Chr 6: 115.92 - 115.96 Mb

Pubmed search

[1]

[2]

Plexin D1, also known as PLXND1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PLXND1 plexin D1.

[edit] Further reading

Ishikawa K, Nagase T, Suyama M, et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 5 (3): 169–76. PMID 9734811.
Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.". Cell 99 (1): 71–80. PMID 10520995.
van der Zwaag B, Hellemons AJ, Leenders WP, et al. (2003). "PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis.". Dev. Dyn. 225 (3): 336–43. doi:10.1002/dvdy.10159. PMID 12412018.
Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMID 12421765.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gitler AD, Lu MM, Epstein JA (2004). "PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.". Dev. Cell 7 (1): 107–16. doi:10.1016/j.devcel.2004.06.002. PMID 15239958.
van der Zwaag B, Verzijl HT, Wichers KH, et al. (2004). "Sequence analysis of the PLEXIN-D1 gene in Möbius syndrome patients.". Pediatr. Neurol. 31 (2): 114–8. doi:10.1016/j.pediatrneurol.2004.02.004. PMID 15301830.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.