Plummer syndrome

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Plummer syndrome is a condition that can occur when a hyper-functioning nodule develops within a longstanding goiter. The result is hyperthyroidism, without the ophthalmologic effects of other conditions with increased levels of thyroid hormones like Grave's disease. These toxic multi or uni-nodular goiters are most common in women over the age of 60. ^[1][2]

Check out Toxic Nodular Goiter. http://www.nlm.nih.gov/medlineplus/ency/article/000317.htm

[edit] References

1. USMLE KAPLAN MEDICAL REVIEW

2. Stedman's Electronic Medical Dictionary