Pleuran

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Pleuran
Identifiers
CAS number [159940-37-1]
Properties
Molar mass 762 kD
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Pleuran is an insoluble polysaccharide (β-(1,3/1,6)-D-glucan), isolated from Pleurotus ostreatus.[1]

Pleuran belongs to a group of glucose polymers commonly called beta-glucans demonstrating biological response modifier properties. These immunomodulating properties render the host more resistant to infections and neoplasms.[2]

Pleuran is also being studied as a potential immunologic adjuvant (Mojžišová et al. 2005).[3]

[edit] References

  1. ^ "Polysaccharides of Pleurotus ostreatus: Isolation and structure of pleuran, an alkali-insoluble β-glucan" (1994). Carbohydrate Polymers 24 (2): 107-111. Elsevier. doi:10.1016/0144-8617(94)90019-1. ISSN 0144-8617. 
  2. ^ Di Luzio, NR (1985). "Update on the immunomodulating activities of glucans". Springer seminars in immunopathology 8 (4): 387-400. Germany: Springer Verlag. ISSN 0344-4325. PMID 4089757. 
  3. ^ (1998). "A Compendium of Vaccine Adjuvants and Excipients". 2nd ed. p. 77. National Institute of Allergy and Infectious Diseases Retrieved on 2008-05-08.