PLEK2
From Wikipedia, the free encyclopedia
Pleckstrin 2
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PDB rendering based on 1v3f. | |||||||||||
Available structures: 1v3f, 1x1g | |||||||||||
Identifiers | |||||||||||
Symbol(s) | PLEK2; | ||||||||||
External IDs | OMIM: 608007 MGI: 1351466 HomoloGene: 8447 | ||||||||||
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RNA expression pattern | |||||||||||
Orthologs | |||||||||||
Human | Mouse | ||||||||||
Entrez | 26499 | 27260 | |||||||||
Ensembl | ENSG00000100558 | ENSMUSG00000021118 | |||||||||
Uniprot | Q9NYT0 | Q9WV52 | |||||||||
Refseq | NM_016445 (mRNA) NP_057529 (protein) |
NM_013738 (mRNA) NP_038766 (protein) |
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Location | Chr 14: 66.92 - 66.95 Mb | Chr 12: 79.81 - 79.83 Mb | |||||||||
Pubmed search | [1] | [2] |
Pleckstrin 2, also known as PLEK2, is a human gene.[1]
[edit] References
[edit] Further reading
- Lemmon MA, Ferguson KM, Abrams CS (2002). "Pleckstrin homology domains and the cytoskeleton.". FEBS Lett. 513 (1): 71-6. PMID 11911883.
- Hamaguchi N, Ihara S, Ohdaira T, et al. (2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading.". Biochem. Biophys. Res. Commun. 361 (2): 270-5. doi: . PMID 17658464.
- Bach TL, Kerr WT, Wang Y, et al. (2007). "PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.". Blood 109 (3): 1147-55. doi: . PMID 17008542.
- Inazu T, Kuroiwa A, Matsuda Y, Miyamoto K (2005). "Cloning, expression and chromosomal assignment of human pleckstrin 2.". Mol. Biol. Rep. 32 (1): 35-40. PMID 15865208.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi: . PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi: . PMID 12477932.
- Inazu T, Yamada K, Miyamoto K (1999). "Cloning and expression of pleckstrin 2, a novel member of the pleckstrin family.". Biochem. Biophys. Res. Commun. 265 (1): 87-93. doi: . PMID 10548495.
- Hu MH, Bauman EM, Roll RL, et al. (1999). "Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement.". J. Biol. Chem. 274 (31): 21515-8. PMID 10419454.
- Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807-28. PMID 8889549.