PLEK2

From Wikipedia, the free encyclopedia


Pleckstrin 2
PDB rendering based on 1v3f.
Available structures: 1v3f, 1x1g
Identifiers
Symbol(s) PLEK2;
External IDs OMIM: 608007 MGI1351466 HomoloGene8447
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 26499 27260
Ensembl ENSG00000100558 ENSMUSG00000021118
Uniprot Q9NYT0 Q9WV52
Refseq NM_016445 (mRNA)
NP_057529 (protein)
NM_013738 (mRNA)
NP_038766 (protein)
Location Chr 14: 66.92 - 66.95 Mb Chr 12: 79.81 - 79.83 Mb
Pubmed search [1] [2]

Pleckstrin 2, also known as PLEK2, is a human gene.[1]


[edit] References

[edit] Further reading

  • Lemmon MA, Ferguson KM, Abrams CS (2002). "Pleckstrin homology domains and the cytoskeleton.". FEBS Lett. 513 (1): 71-6. PMID 11911883. 
  • Hamaguchi N, Ihara S, Ohdaira T, et al. (2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading.". Biochem. Biophys. Res. Commun. 361 (2): 270-5. doi:10.1016/j.bbrc.2007.06.132. PMID 17658464. 
  • Bach TL, Kerr WT, Wang Y, et al. (2007). "PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.". Blood 109 (3): 1147-55. doi:10.1182/blood-2006-02-001339. PMID 17008542. 
  • Inazu T, Kuroiwa A, Matsuda Y, Miyamoto K (2005). "Cloning, expression and chromosomal assignment of human pleckstrin 2.". Mol. Biol. Rep. 32 (1): 35-40. PMID 15865208. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Inazu T, Yamada K, Miyamoto K (1999). "Cloning and expression of pleckstrin 2, a novel member of the pleckstrin family.". Biochem. Biophys. Res. Commun. 265 (1): 87-93. doi:10.1006/bbrc.1999.1461. PMID 10548495. 
  • Hu MH, Bauman EM, Roll RL, et al. (1999). "Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement.". J. Biol. Chem. 274 (31): 21515-8. PMID 10419454. 
  • Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807-28. PMID 8889549.