PLAC1

From Wikipedia, the free encyclopedia

Placenta-specific 1

Identifiers

External IDs

OMIM: 300296 MGI: 1926287 HomoloGene: 11039

Gene ontology
Molecular Function:	• molecular_function
Cellular Component:	• cellular_component
Biological Process:	• placenta development • multicellular organismal development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_021796 (mRNA)
NP_068568 (protein)

NM_019538 (mRNA)
NP_062411 (protein)

Location

Chr X: 133.53 - 133.62 Mb

Chr X: 49.31 - 49.36 Mb

Pubmed search

[1]

[2]

Placenta-specific 1, also known as PLAC1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PLAC1 placenta-specific 1.

[edit] Further reading

Cocchia M, Huber R, Pantano S, et al. (2000). "PLAC1, an Xq26 gene with placenta-specific expression.". Genomics 68 (3): 305–12. doi:10.1006/geno.2000.6302. PMID 10995572.
Fant M, Weisoly DL, Cocchia M, et al. (2003). "PLAC1, a trophoblast-specific gene, is expressed throughout pregnancy in the human placenta and modulated by keratinocyte growth factor.". Mol. Reprod. Dev. 63 (4): 430–6. doi:10.1002/mrd.10200. PMID 12412044.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Concu M, Banzola I, Farina A, et al. (2005). "Rapid clearance of mRNA for PLAC1 gene in maternal blood after delivery.". Fetal. Diagn. Ther. 20 (1): 27–30. doi:10.1159/000081365. PMID 15608456.
Massabbal E, Parveen S, Weisoly DL, et al. (2005). "PLAC1 expression increases during trophoblast differentiation: evidence for regulatory interactions with the fibroblast growth factor-7 (FGF-7) axis.". Mol. Reprod. Dev. 71 (3): 299–304. doi:10.1002/mrd.20272. PMID 15803460.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Fujito N, Samura O, Miharu N, et al. (2007). "Increased plasma mRNAs of placenta-specific 1 (PLAC1) and glial cells-missing 1 (GCM1) in mothers with pre-eclampsia.". Hiroshima J. Med. Sci. 55 (1): 9–15. PMID 16594548.
Rizzo N, Banzola I, Concu M, et al. (2007). "PLAC1 mRNA levels in maternal blood at induction of labor correlate negatively with induction-delivery interval.". Eur. J. Obstet. Gynecol. Reprod. Biol. 132 (2): 177–81. doi:10.1016/j.ejogrb.2006.05.039. PMID 16860456.
Fant M, Barerra-Saldana H, Dubinsky W, et al. (2007). "The PLAC1 protein localizes to membranous compartments in the apical region of the syncytiotrophoblast.". Mol. Reprod. Dev. 74 (7): 922–9. doi:10.1002/mrd.20673. PMID 17186554.
Purwosunu Y, Sekizawa A, Farina A, et al. (2007). "Cell-free mRNA concentrations of CRH, PLAC1, and selectin-P are increased in the plasma of pregnant women with preeclampsia.". Prenat. Diagn. 27 (8): 772–7. doi:10.1002/pd.1780. PMID 17554801.
Koslowski M, Sahin U, Mitnacht-Kraus R, et al. (2007). "A placenta-specific gene ectopically activated in many human cancers is essentially involved in malignant cell processes.". Cancer Res. 67 (19): 9528–34. doi:10.1158/0008-5472.CAN-07-1350. PMID 17909063.