PKN3 (gene)

From Wikipedia, the free encyclopedia

Protein kinase N3

Identifiers

PKN3; RP11-545E17.1

External IDs

OMIM: 610714 MGI: 2388285 HomoloGene: 50980

Gene ontology
Molecular Function:	• nucleotide binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• intracellular • nucleus • Golgi apparatus
Biological Process:	• protein amino acid phosphorylation • signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_013355 (mRNA)
NP_037487 (protein)

NM_153805 (mRNA)
NP_722500 (protein)

Location

Chr 9: 130.5 - 130.52 Mb

Chr 2: 29.9 - 29.91 Mb

Pubmed search

[1]

[2]

Protein kinase N3, also known as PKN3, is a human gene.^[1]

[edit] References

^ Entrez Gene: PKN3 protein kinase N3.

[edit] Further reading

Wissing J, Jänsch L, Nimtz M, et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.". Mol. Cell Proteomics 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Leenders F, Möpert K, Schmiedeknecht A, et al. (2005). "PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.". EMBO J. 23 (16): 3303–13. doi:10.1038/sj.emboj.7600345. PMID 15282551.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMID 15164053.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Shibata H, Oishi K, Yamagiwa A, et al. (2001). "PKNbeta interacts with the SH3 domains of Graf and a novel Graf related protein, Graf2, which are GTPase activating proteins for Rho family.". J. Biochem. 130 (1): 23–31. PMID 11432776.
Oishi K, Takahashi M, Mukai H, et al. (2001). "PKN regulates phospholipase D1 through direct interaction.". J. Biol. Chem. 276 (21): 18096–101. doi:10.1074/jbc.M010646200. PMID 11259428.
Oishi K, Mukai H, Shibata H, et al. (1999). "Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.". Biochem. Biophys. Res. Commun. 261 (3): 808–14. doi:10.1006/bbrc.1999.1116. PMID 10441506.