PITRM1

From Wikipedia, the free encyclopedia

Pitrilysin metallopeptidase 1

Identifiers

PITRM1; MP1; KIAA1104; MGC138192; MGC141929; hMP1

External IDs

MGI: 1916867 HomoloGene: 5742

Gene ontology
Molecular Function:	• metalloendopeptidase activity • enzyme activator activity • zinc ion binding • metal ion binding
Cellular Component:	• mitochondrion • mitochondrial matrix
Biological Process:	• proteolysis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014889 (mRNA)
NP_055704 (protein)

NM_145131 (mRNA)
NP_660113 (protein)

Location

Chr 10: 3.17 - 3.2 Mb

Chr 13: 6.55 - 6.58 Mb

Pubmed search

[1]

[2]

Pitrilysin metallopeptidase 1, also known as PITRM1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PITRM1 pitrilysin metallopeptidase 1.

[edit] Further reading

Falkevall A, Alikhani N, Bhushan S, et al. (2006). "Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP.". J. Biol. Chem. 281 (39): 29096-104. doi:10.1074/jbc. M602532200. PMID 16849325.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Kikuno R, Nagase T, Ishikawa K, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (3): 197-205. PMID 10470851.
Mzhavia N, Berman YL, Qian Y, et al. (1999). "Cloning, expression, and characterization of human metalloprotease 1: a novel member of the pitrilysin family of metalloendoproteases.". DNA Cell Biol. 18 (5): 369-80. doi:10.1089/104454999315268. PMID 10360838.
Schaeffer HJ, Catling AD, Eblen ST, et al. (1998). "MP1: an MEK binding partner that enhances enzymatic activation of the MAP kinase cascade.". Science 281 (5383): 1668-71. PMID 9733512.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807-28. PMID 8889549.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Marusov EV (1977). "[Ecological sterotypes of defensive behavior in fish under the action of chemical danger signals]". Nauchnye doklady vyssheĭ shkoly. Biologicheskie nauki (8): 67-9. PMID 1036083.