Pimeloyl-CoA dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a pimeloyl-CoA dehydrogenase (EC 1.3.1.62) is an enzyme that catalyzes the chemical reaction

pimeloyl-CoA + NAD⁺ 6-carboxyhex-2-enoyl-CoA + NADH + H⁺

Thus, the two substrates of this enzyme are pimeloyl-CoA and NAD⁺, whereas its 3 products are 6-carboxyhex-2-enoyl-CoA, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is pimeloyl-CoA:NAD+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

[edit] References

• IUBMB entry for 1.3.1.62
• BRENDA references for 1.3.1.62 (Recommended.)
• PubMed references for 1.3.1.62
• PubMed Central references for 1.3.1.62
• Google Scholar references for 1.3.1.62
• Gallus C, Schink B (1994). "Anaerobic degradation of pimelate by newly isolated denitrifying bacteria". Microbiology. 140: 409–16. PMID 8180704. 

[edit] External links

• IUBMB entry for 1.3.1.62

• KEGG entry for 1.3.1.62

• BRENDA entry for 1.3.1.62

• NiceZyme view of 1.3.1.62

• EC2PDB: PDB structures for 1.3.1.62

• PRIAM entry for 1.3.1.62

• PUMA2 entry for 1.3.1.62

• IntEnz: Integrated Enzyme entry for 1.3.1.62

• MetaCyc entry for 1.3.1.62

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018515: pimeloyl-CoA dehydrogenase

• AMIGO entry for GO code 0018515: pimeloyl-CoA dehydrogenase