Pimelic acid

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Pimelic acid
Pimelic acid
IUPAC name heptanedioic acid
Identifiers
CAS number [111-16-0]
SMILES OC(=O)CCCCCC(=O)O
Properties
Molecular formula C7H12O4
Molar mass 160 g/mol
Density 1.28 g/cm3
Melting point

103-105 °C

Boiling point

Decomposes

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Pimelic acid is the organic compound with the formula HO2C(CH2)5CO2H. Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine. Pimelic acid is one methylene longer than a related dicarboxylic acid, adipic acid, a precursor to many polyesters and polyamides.

Pimelic acid has been synthesized from cyclohexanone and from salicylic acid.[1] In the former route, the additional carbon is suppled by dimethyloxalate, which reacts with the enolate.

[edit] References

  1. ^ Snyder, H. R.; Brooks, A. L.; Shapiro, S. H. "Pimelic Acid from Cyclohexanone" and Müller, A. "Pimelic Acid from Salicylic Acid" Organic Syntheses, Collected Volume 2, p.531 (1943).http://www.orgsyn.org/orgsyn/pdfs/CV2P0531.pdf