PIK3R5

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Phosphoinositide-3-kinase, regulatory subunit 5, p101
Identifiers
Symbol(s) PIK3R5; F730038I15Rik; FOAP-2; P101-PI3K
External IDs MGI: 2443588 HomoloGene: 8627
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 23533 320207
Ensembl ENSG00000141506 ENSMUSG00000020901
Uniprot Q8WYR1 A1A4T4
Refseq NM_014308 (mRNA)
NP_055123 (protein)		 NM_177320 (mRNA)
NP_796294 (protein)
Location Chr 17: 8.72 - 8.76 Mb Chr 11: 68.25 - 68.31 Mb
Pubmed search [1] [2]

Phosphoinositide-3-kinase, regulatory subunit 5, p101, also known as PIK3R5, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5, p101.

[edit] Further reading

  • Johnson C, Marriott SJ, Levy LS (2007). "Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival.". Oncogene 26 (49): 7049–57. doi:10.1038/sj.onc.1210504. PMID 17486067. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Suire S, Coadwell J, Ferguson GJ, et al. (2005). "p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.". Curr. Biol. 15 (6): 566–70. doi:10.1016/j.cub.2005.02.020. PMID 15797027. 
  • Voigt P, Brock C, Nürnberg B, Schaefer M (2005). "Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma.". J. Biol. Chem. 280 (6): 5121–7. doi:10.1074/jbc.M413104200. PMID 15611065. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Brock C, Schaefer M, Reusch HP, et al. (2003). "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma.". J. Cell Biol. 160 (1): 89–99. doi:10.1083/jcb.200210115. PMID 12507995. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Metjian A, Roll RL, Ma AD, Abrams CS (1999). "Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus.". J. Biol. Chem. 274 (39): 27943–7. PMID 10488142. 
  • Krugmann S, Hawkins PT, Pryer N, Braselmann S (1999). "Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits.". J. Biol. Chem. 274 (24): 17152–8. PMID 10358071. 
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