Picolinic acid
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| Picolinic acid | |
|---|---|
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| IUPAC name | pyridine-2-carboxylic acid |
| Identifiers | |
| CAS number | [98-98-6] |
| PubChem | |
| SMILES | C1=CC=NC(=C1)C(=O)O |
| Properties | |
| Molecular formula | C6H5NO2 |
| Molar mass | 123.109 |
| Appearance | White to tan crystalline solid |
| Melting point |
136 - 138 C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Picolinic acid is a pyridine compound with a carboxyl side chain at the 2-position. It is an isomer of nicotinic acid, which has the carboxyl side chain at the 3-position. Picolinic acid acts as a chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body. It is involved in phenylalanine, tryptophan, and alkaloid production, and for the quantitative detection of calcium. This forms a complex with zinc, that may facilitate the passage of zinc through the gastrointestinal wall and into the circulatory system. Commercially available picolinic acid is used as an intermediate to produce pharmaceuticals (especially local anesthetics) and metal salts for the application of nutritional supplements.
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