Phylloquinone monooxygenase (2,3-epoxidizing)

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In enzymology, a phylloquinone monooxygenase (2,3-epoxidizing) (EC 1.14.99.20) is an enzyme that catalyzes the chemical reaction

phylloquinone + AH2 + O2 \rightleftharpoons 2,3-epoxyphylloquinone + A + H2O

The 3 substrates of this enzyme are phylloquinone, AH2, and O2, whereas its 3 products are 2,3-epoxyphylloquinone, A, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing). Other names in common use include phylloquinone epoxidase, vitamin K 2,3-epoxidase, vitamin K epoxidase, and vitamin K1 epoxidase.

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The CAS registry number for this enzyme class is 54596-37-1.

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