Phosphoglycolate phosphatase

From Wikipedia, the free encyclopedia

In enzymology, a phosphoglycolate phosphatase (EC 3.1.3.18) is an enzyme that catalyzes the chemical reaction

2-phosphoglycolate + H₂O glycolate + phosphate

Thus, the two substrates of this enzyme are 2-phosphoglycolate and H₂O, whereas its two products are glycolate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 2-phosphoglycolate phosphohydrolase. Other names in common use include phosphoglycolate hydrolase, 2-phosphoglycolate phosphatase, P-glycolate phosphatase, and phosphoglycollate phosphatase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1TE2, 1WR8, 2HDO, 2HI0, and 2NYV.

[edit] References

• IUBMB entry for 3.1.3.18
• BRENDA references for 3.1.3.18 (Recommended.)
• PubMed references for 3.1.3.18
• PubMed Central references for 3.1.3.18
• Google Scholar references for 3.1.3.18
• Christeller JT, Tolbert NE (1978). "Phosphoglycolate phosphatase. Purification and properties". J. Biol. Chem. 253: 1780–5. PMID 204630. 

[edit] External links

The CAS registry number for this enzyme class is 9025-76-7.

• IUBMB entry for 3.1.3.18

• KEGG entry for 3.1.3.18

• BRENDA entry for 3.1.3.18

• NiceZyme view of 3.1.3.18

• EC2PDB: PDB structures for 3.1.3.18

• PRIAM entry for 3.1.3.18

• PUMA2 entry for 3.1.3.18

• IntEnz: Integrated Enzyme entry for 3.1.3.18

• MetaCyc entry for 3.1.3.18

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008967: phosphoglycolate phosphatase

• AMIGO entry for GO code 0008967: phosphoglycolate phosphatase