Phosphoglucokinase

From Wikipedia, the free encyclopedia

In enzymology, a phosphoglucokinase (EC 2.7.1.10) is an enzyme that catalyzes the chemical reaction

ATP + alpha-D-glucose 1-phosphate ADP + alpha-D-glucose 1,6-bisphosphate

Thus, the two substrates of this enzyme are ATP and alpha-D-glucose 1-phosphate, whereas its two products are ADP and alpha-D-glucose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase. Other names in common use include glucose-phosphate kinase, phosphoglucokinase (phosphorylating), and ATP:D-glucose-1-phosphate 6-phosphotransferase. This enzyme participates in starch and sucrose metabolism.

[edit] References

• IUBMB entry for 2.7.1.10
• BRENDA references for 2.7.1.10 (Recommended.)
• PubMed references for 2.7.1.10
• PubMed Central references for 2.7.1.10
• Google Scholar references for 2.7.1.10
• CE (1949). "The enzymatic synthesis of glucose-1,6-diphosphate". Arch. Biochem. 23: 55–66. 

[edit] External links

The CAS registry number for this enzyme class is 9032-96-6.

• IUBMB entry for 2.7.1.10

• KEGG entry for 2.7.1.10

• BRENDA entry for 2.7.1.10

• NiceZyme view of 2.7.1.10

• EC2PDB: PDB structures for 2.7.1.10

• PRIAM entry for 2.7.1.10

• PUMA2 entry for 2.7.1.10

• IntEnz: Integrated Enzyme entry for 2.7.1.10

• MetaCyc entry for 2.7.1.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050190: phosphoglucokinase

• AMIGO entry for GO code 0050190: phosphoglucokinase